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KMID : 0359019850050010067
Korean Journal of Gastrointestinal Endoscopy
1985 Volume.5 No. 1 p.67 ~ p.71
Pseudomembranous Colitis Caused by Clostridium Difficile
Á¶¼º¹Î/Cho SM
ÀÌâµ·/À̿ϱ¹/Á¤ÀνÄ/±è°æÈñ/Á¤±Ô¿ø/¼±Èñ½Ä/Á¤È¯±¹/Lee CD/Lee WK/Chung IS/Kim KH/Chung KW/Sun HS/Chung
Abstract
Pseudomembranous colitis (PMC) was first described by Finney as postoperative diphtheritic enteritis in 1893 and was known to be associated with antibiotics by Reiner et al in 1952. Most cases of antibiotic-associated PMC are now associated with cytotoxigenic C. difficile. The association of PMC several antibiotics is well docamented; however, its association with clindamycin appeared to be most striking. We experienced a male patient who developed tarry stool, abdominal pain and diarrhea after having recieved clindamycin for two weeks. The PMC diagnosed by colonofiberscopy with biopsy and C. difficile was identified by tissue-culture study. The patient was treated by oral vancomycin and healed. Described here a case of PMC with some review of literature.
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